Clomiphene treatment

Clomiphene Citrate was the original ‘fertility pill’, and it is still widely used. It’s the most ‘natural’ scientifically proven fertility treatment – no injections, and you still have sex to become pregnant.

Clomiphene is mainly used for two groups of people:

  • Women who don’t ovulate or who have irregular cycles.
  • Women with a shorter duration of unexplained infertility.

Letrozole treatment

Letrozole is a new alternative for women who don’t ovulate or have irregular cycles. Overall, about 20-30% of women aged 37 and under have a child over a course of up to 3-4 cycles of Clomiphene or Letrozole.

There is a slightly increased chance of twins, which can be reduced to around 5–10% by checking the body’s response to the medication using a blood test or an ultrasound scan.

How it works


Ovulation Induction with FSH

OI with FSH may be an option for women who don't ovulate, who don't respond or become pregnant using the above OI treatments. You can read more about it here in our Pathways booklet.